One of its primary functions is to help generate energy in your cells. Its other crucial role is to serve as an antioxidant and protect cells from oxidative damage 2 , 5.
Excessive amounts of free radicals lead to oxidative damage, which can interfere with regular cell functioning. This is known to cause many health conditions 6. CoQ10 is present in every cell of your body. However, the highest concentrations are found in organs with the greatest energy demands, such as the heart, kidneys, lungs and liver 7.
Heart failure is often a consequence of other heart conditions, such as coronary artery disease or high blood pressure 8. These conditions can lead to increased oxidative damage and inflammation of the veins and arteries 8 , 9.
Heart failure occurs when these problems affect the heart to the point that it is unable to regularly contract, relax or pump blood through the body 8.
To make matters worse, some treatments for heart failure have undesirable side effects, such as low blood pressure, while others could even further reduce CoQ10 levels In a study of people with heart failure, treatment with CoQ10 for two years improved their symptoms and reduced their risk of dying from heart problems Also, another study treated people with CoQ10 or a placebo for a year.
At the end of the study, those in the CoQ10 group had been hospitalized less frequently for worsening heart failure and had fewer serious complications It seems that treatment with CoQ10 could assist with restoring optimal levels of energy production, reduce oxidative damage and improve heart function, all of which can aid the treatment of heart failure 8. Summary: CoQ10 seems to help treat heart failure by improving heart function, increasing ATP production and limiting oxidative damage.
Female fertility decreases with age due to a decline in the number and quality of available eggs. CoQ10 is directly involved in this process. As you age, CoQ10 production slows, making the body less effective at protecting the eggs from oxidative damage Supplementing with CoQ10 seems to help and may even reverse this age-related decline in egg quality and quantity.
Similarly, male sperm is susceptible to the effects of oxidative damage, which may result in reduced sperm count, poor sperm quality and infertility 14 , Several studies have concluded that supplementing with CoQ10 may improve sperm quality, activity and concentration by increasing antioxidant protection 15 , Summary: The antioxidant properties of CoQ10 could help improve sperm quality and reduce the decline in the number and quality of eggs in women.
These agents can be internal or external. Some internal damaging factors include cellular damage and hormonal imbalances. External factors include environmental agents, such as UV rays Harmful elements can lead to reduced skin moisture and protection from environmental aggressors, as well as the thinning of the layers of the skin 17 , Applying CoQ10 directly to the skin can reduce the damage from internal and external agents by increasing energy production in skin cells and promoting antioxidant protection In fact, CoQ10 applied directly to the skin has been shown to reduce oxidative damage caused by UV rays and even decrease the depth of wrinkles Lastly, people with low levels of CoQ10 seems to be more likely to develop skin cancer Summary: When applied directly to the skin, CoQ10 can reduce sun damage and increase antioxidant protection.
Levels of CoQ10 in your body decrease as you age. CoQ10 levels have also been found to be lower in people with certain conditions, such as heart disease, and in those who take cholesterol-lowering drugs called statins. CoQ10 is found in meat, fish and nuts. The amount of CoQ10 found in these dietary sources, however, isn't enough to significantly increase CoQ10 levels in your body. CoQ10 dietary supplements are available as capsules, chewable tablets, liquid syrups, wafers and by IV.
CoQ10 might help prevent or treat certain heart conditions, as well as migraine headaches. Research on CoQ10 use for specific conditions and activities shows:. CoQ10 supplements might be beneficial for treating conditions such as congestive heart failure and preventing migraines. CoQ10 is considered safe, with few side effects. However, be sure to take this supplement under your doctor's supervision.
CoQ10 supplements appear to be safe and to produce few side effects when taken as directed. The safety of use of CoQ10 during pregnancy and breast-feeding hasn't been established. Don't use CoQ10 if you're pregnant or breast-feeding without your doctor's approval. There is a problem with information submitted for this request. Coenzyme Q10, or CoQ10, is a naturally occurring chemical that exists in almost every cell of the human body. CoQ10 carries out several vital roles, including promoting energy production and neutralizing harmful particles called free radicals.
People can get CoQ10 through foods and supplements. CoQ10 is an essential nutrient present in almost every cell of the human body. The following foods also contain CoQ CoQ10 plays a vital role in energy production and DNA replication and repair. It also acts as an antioxidant , neutralizing harmful free radicals. For the body to use CoQ10, it must convert it from its inactive form, ubiquinone, into it its active form, ubiquinol.
This process is known as ATP synthesis. Under normal conditions, free radicals regulate communication between cells and defend the body against infectious microbes. However, excess free radicals cause DNA damage, which can lead to the following:. CoQ10 acts as an antioxidant by neutralizing free radicals. Standard daily doses of CoQ10 range from 60 milligrams mg to mg.
The highest recommended dose is 1, mg. However, clinical trials have used dosages as high as 3, mg per day. Different types of CoQ10 supplements may also require different dosages. Most supplements contain the inactive form of CoQ10, ubiquinone, which is harder to absorb than ubiquinol. A randomized trial compared the effects of mg daily doses of ubiquinone and ubiquinol supplements on CoQ10 levels in older men.
Ubiquinol supplementation led to a 1. Supplements containing ubiquinone did not have a significant effect on CoQ10 levels. CoQ10 protects cells against oxidative damage. CoQ10 could, therefore, provide a range of health benefits. Some examples include:. The heart contains some of the highest concentrations of CoQ10 in the body. The vast majority of people with heart disease also have low CoQ10 levels. Researchers now consider low CoQ10 levels to be an indicator of the severity and long term outcome of various heart diseases.
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